September 26, 2022

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A study provides clues as to who is at risk for long-term COVID

A study published in the January 25 issue of the journal Nature Communications found that people with chronic COVID levels had low levels of certain antibodies in their blood.

Recent study by scientists University Hospital of Zurich, SwitzerlandGave clues about the causes of chronic coma that many people suffer from after being infected with the SARS-CoV-2 virus, which will allow the development of diagnostic methods.

The study was published in the journal Jan. 25 Natural contactIndividuals diagnosed with chronic goiter Shortly after being infected with the corona virus, they have low levels of certain antibodies in their blood.

This finding could help determine a person’s risk of developing chronic goiter in the future, new research suggests.

If confirmed by major studies, the findings could help scientists create a test to predict Symptoms may persist for weeks, months, or years after infection.

“We want to identify and identify as soon as possible those at risk of developing chronic goiter,” said Dr. Onur Boyman, author of the new study and researcher in the Department of Immunology at the University of Zurich Hospital. .

Longcovit, or Longcovit, is a condition that is not yet well understood, has no definitive diagnosis or treatment, and has confused physicians and researchers around the world since the onset of the corona virus infection.

The exact number of long-term Govt patients is unclear, although at least in the United States, Overall, one-third of COVID-19 patients experience symptoms for at least a month.

External experts said that in the absence of available information yet, any way to allow so-called long-term patients to be diagnosed early is welcome. NBC News.

Charles Downs is a longtime Govt researcher and associate professor at the University of Miami Nursing and Health Studies. The research is “very promising”.

New research suggests that this finding could help a person's risk of developing chronic goiter in the future (EFE / Andre Coelho)
New research suggests that this finding could help a person’s risk of developing chronic goiter in the future (EFE / Andre Coelho)

“There is no single test, no imaging test to diagnose chronic goiter,” he said. “It helps us move in that direction.”

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Boyman’s research began in early 2020, during the first wave of the epidemic. His team followed the patients through the acute phase of the infection, followed by a six-month, then-year-long covid event that became apparent.

He added that several key differences emerged when comparing more than 500 Covit-19 patients, some of whom had long-term Covit and some symptoms resolved.

It is very obvious how the immune system of patients who developed chronic goiter initially reacted to the virus.

These patients in Boyman’s study Two showed a significant decrease in the levels of immunoglobulins, IgM and IgG3, which are antibodies produced by the immune system to fight infection. In healthy immune systems, the levels of these immunoglobulins increase when they are exposed to an infection.

Those levels of antibodies, Combined with other factors such as middle age and history of asthma, They were 75% effective in predicting the durable Govt, Boyman said.

This is because researchers have long known which patients have goiter. Further research is needed to determine whether the criteria are accurate from the onset of the disease.

“These individuals may initially have a disability, and then due to their asthma background, they may react slightly differently to viruses, which can lead to a false immune response,” he said.

Downs University of Miami said in his experience, Many patients with chronic goiter have some other history of asthma or allergic diseases. Such as chronic runny nose related to seasonal allergies.

If confirmed in major studies, “this research will be an important step in sending evidence from post-Govt-19 clinics to those most in need,” said Dr. Karthik Sehgal, a longtime Govt researcher who specializes in Dana-Farber’s clinical oncology. , Boston Cancer Institute.

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There is some information to be taken into account in the research conducted in Zurich to strengthen the opinion of scientists that further studies are necessary. Prior to the establishment of the Omigran variant, patients in the study were infected between April 2020 and August 2021.

Therefore, it is not clear whether these findings apply to those who may develop cov- eral long after the new variant infection was discovered in South Africa last November.

“It’s important to see if these markers are a prognosis for those who have been vaccinated because more people in the world have been vaccinated or have been infected with a previous infection,” he said (Getty Images).

In addition, the vaccine status of the study participants was not taken into account.Even before vaccines became available, in the early 2020s, many chronic Govt patients became ill.

“It’s important to see if these markers are a prognosis for those who have been vaccinated because more people in the world have been vaccinated or have had a previous infection.” Said in a statement Claire Steves, Senior Medical Professor at King’s College London.

But Steves, who is not involved in the new research, said “more people are at risk of developing long-term symptoms because the cases are still high.” “We urgently need to increase research on how to prevent this from happening.”

Since the onset of the infection, it is known that loss of sense of smell and taste may be one of the mild symptoms of COVID-19. Various studies show that 80% of people recover capacity in about a month. But there are others that can’t even smell or taste for six months or more. Even a few can never regain those two senses.

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Although uncomfortable, it is also one of the many health conditions that can last a long time after a case of new corona virus. Called “COVID extends longevity”, The event is classified Weak symptoms such as What Shortness of breath, severe fatigue, fever, dizziness, confusion, diarrhea, palpitations, muscle and abdominal pain, mood swings and difficulty sleeping.

Acute forms of chronic COVID can damage the lungs, heart and kidneys. It can also affect your mental health. In addition, they may qualify for a disability. “We are still trying to understand the enduring covid. I will not be so quick to get infected with the natural virus because we do not fully understand it yet,” he said days ago. Milk aphid, Director of the Center for Vaccine Education at the Children’s Hospital in Philadelphia and consultant to the White House on Infections.

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